Molecular Details
DICL_CP_0312371
- lead(2+)
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0312371
PubChem CID
Molecular Formula
Pb+2 Molecular Weight
207.2 g/mol
Synonyms/Alias
[Lead(2+); Lead (II) ion; Lead(2+) ion; Lead; ion (Pb2+); 14280-50-3; Pb2+; Pb(2+); Lead ion; Lead(2+)ions; Lead(2+) ions; Lead-239; Lead; isotope of mass 239; Omaha; 239Pb; PbII; Lead(II); Lead ion (...
InChI Key
RVPVRDXYQKGNMQ-UHFFFAOYSA-N
InChI
InChI=1S/Pb/q+2
IUPAC Name
lead(2+)
CAS Number
7439-92-1
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
1 0 0 0 0 0 0 0 0 0999 V2000
0.0000 0.0000 0.0000 Pb 0 0 0 0 0 15 0 0 0 0 0 0
M CHG 1 1 2
M END
$$$$
Experimental Data
Activity Data
Target Ion Channel
epithelial calcium channel (ECaC1)
Uniprot Accession Number
Function
Blocker
Species
Homo sapiens (Human)
IC50
IC50: 1050 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)
Experimental Conditions
pH
pH 7.4
Holding Potential
−150 to 100 mV mV
Temperature
20−22 °C
Test Method
Patch-clamping
Test Species
Not specified
Binding Information
Binding Site
Not specified
Binding Site Residue
Not specified
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
1
Rotatable Bonds
0
logP
-0.3808
Complexity
5.754
TPSA (Ų)
0
H-Bond Donors
0
H-Bond Acceptors
0
Ring Count
0